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Migraine is a distinct neurological condition, setting itself apart from common headaches. An onset of a migraine attack is abrupt, characterized by intense pain localized to one side of the head.1,2 The severity of this pain surpasses that of conventional headaches and is often accompanied by a constellation of supplementary symptoms.1


For diagnosis of migraine, the characteristic symptoms must manifest at least five times over time.1
 




The ramifications of migraine on daily life can be profound. While some individuals experience sporadic attacks, others endure multiple episodes per month.1


Clinical Overview

Understanding More About Signs and Symptoms

Migraines hallmark moderate to severe unilateral headaches. Described as pulsatile or throbbing, the pain escalates with physical activity or even minor movements.1
Concurrently, symptoms such as nausea, vomiting, and photophobia may arise. In pediatric cases, children might exhibit non-headache symptoms such as dizziness, nausea, or vomiting.1,3
Sensitivity to light and sound is also common during migraine episodes. If left untreated, the symptoms, the symptoms persist for four hours to three days.1,2
Preceding the migraine, certain individuals experience auras, paving the way for typical migraine symptoms.1,4


Predisposing Factors of Migraines

Exploring the Causes and the Associated Long-Term Effects

 

Migraine's precise etiology remains elusive, with theories implicating vascular inflammation and altered pain signal processing.1,5
Stress, a crucial pain modulator, often exacerbates the condition.
Prolonged stress or inadequate breaks could elevate migraine risk.1,6
Interestingly, migraines might manifest during periods of stress relief, such as weekends or early vacations.7

 

Disrupted sleep and eating patterns can also trigger migraines.8
Notably, the interplay of diet, exercise, and migraines suggest a potential relationship. Tracking triggers via a migraine diary aids in uncovering personalized connections.1


Existing Situation vs. the Future

Evaluating Prevalence for a Better Future

 

Migraines exhibit a higher prevalence in females than males.
Approximately 14 in 100 women and 7 in 100 men experience recurring migraines. Conversely, childhood cases impact boys and girls equally, affecting around 4 to 5 in 100 children.1

 

In certain instances, migraines wane naturally over time. Adolescent females might experience their initial migraines upon menarche.
Many women observe an attenuation of attacks during pregnancy and their eventual cessation post-menopause.
Chronic migraines, characterized by headaches exceeding 15 days per month for over three months, are rare.1


References

1. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Migraine: Overview. [Updated 2018 May 30]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279373/
2. “Headache.” National Institute of Neurological Disorders and Stroke, U.S. Department of Health and Human Services, www.ninds.nih.gov/healthinformation/disorders/headache#:~:text=Migraine%20headaches%20are%20characterized%20by,from%20
four%20to%2072%20hours
. Accessed 30 Aug. 2023.
3. “Pediatric Migraines - Conditions and Treatments: Children’s National Hospital.” Conditions and Treatments | Children’s National Hospital, childrensnational.org/visit/conditions-and-treatments/brain--nervous-system/migraines. Accessed 30 Aug. 2023.
4. Shankar Kikkeri N, Nagalli S. Migraine With Aura. [Updated 2022 Dec 6]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554611/
5. Shevel, E., (2011). The extracranial vascular theory of migraine—a great story confirmed by the facts. Headache: The Journal of Head and Face Pain, 51(3), pp.409-417.
6. Maleki, N., Becerra, L. and Borsook, D. (2012). Migraine: maladaptive brain responses to stress. Headache: The Journal of Head and Face Pain, 52, pp.102-106.
7. Lipton, R.B., Buse, D.C., Hall, C.B., Tennen, H., DeFreitas, T.A., Borkowski, T.M., Grosberg, B.M. and Haut, S.R. (2014). Reduction in perceived stress as a migraine trigger: testing the “let-down headache” hypothesis. Neurology, 82(16), pp.1395-1401.
8. “Can a Lack of Sleep Cause Headaches?” Sleep Foundation, 13 Feb. 2023, www.sleepfoundation.org/sleep-deprivation/sleep-deprivation-and migraines#:~:text=during%20the%20week.-,The%20relationship%20between%20sleep%20deprivation%20and%20migraines,disrupt
%20the%20sleep%2Dwake%20cyc



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