A Legacy of Innovation

We have taken bold steps to shape the landscape in inflammatory bowel disease (IBD) management, striving to help patients achieve a better tomorrow. But we have more work to do. We are relentless in our quest to better understand patient needs and will continue to work closely with patients and partners to advance the quality of care in IBD.

Learn more about our gastroenterology focus areas:

Pioneers in Science

Leaving No Patient Behind

As we learn more about pathophysiology and optimal disease management we can set more ambitious goals for tackling IBD in ways that extend beyond symptoms. For example, tools like our IBD Disk and the Lémann score help us monitor more IBD patients to identify those with a poor prognosis. Unlocking effective treatment strategies is vital to helping modify the course of the disease.

Addressing Unmet Needs

We currently have over 30 ongoing or planned trials in IBD. By learning, adapting and innovating, AbbVie aspires to make IBD patients’ long-term goals possible. 

Partnerships with Purpose

We work with partners to tackle global challenges in IBD and shape the future of disease management. Together, we aim to enhance quality of care by educating on Treat to Target (T2T), demonstrating its clinical and economic impact, and making non-invasive monitoring standard for most patients.

Key Pathways


TNF- α

A cytokine that contributes to the induction and maintenance of the inflammatory immune response.


A cytokine that shares a subunit with IL-12 and works to mediate inflammatory responses.


An enzyme that signals and initiates the response of other cytokines involved in the body’s immune response.


A protein receptor expressed by B cells, macrophages and dendritic cells that is involved in mediating inflammatory responses.

Learn more about how we are moving science forward.

Committed to Gastroenterology

Then and Now: I won't be defined by my Chron's Disease

A letter from the future offers perspective and advice on living with Crohn’s disease. 

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