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      Aim for deep response (uMRD) as part of your patients' treatment goals

      Science of deep response

      Achieving deep response early can help improve survival outcomes for patients with CLL1-3

      Deep response, or undetectable minimal residual disease (uMRD), is defined as <1 tumour cell per 104 white cells. It is a powerful prognostic tool that demonstrates an inverse relationship with patient outcomes.1

      How low can you go?

      Select a patient to see how choosing a treatment capable of achieving deep response could improve their outcomes1

      Hypothetical scenarios of CLL burden during and after therapy.
      Adapted from Bottcher et al, 2013.1
      CLL = chronic lymphocytic leukaemia; MRD = minimal residual disease.


      Survival benefits


      1. Böttcher S, et al. Hematol Oncol Clin North Am. 2013;27(2):267-288.
      2. Kwok M, et al. Blood 2016;128: 2770–2773.
      3. Langerak AW, et al. Blood 2019;133(Suppl.): 494–497.



      Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk.

      Adverse events should also be reported to AbbVie on GBPV@abbvie.com

      UK-VNCCLL-200348. Date of preparation: October 2020.