This promotional material is intended for UK Healthcare Professionals only.
BOTOX® (botulinum toxin type A) Prescribing Information and adverse event reporting information can be found below.
Guidelines recommend BOTOX® as a treatment option in the management of post-stroke spasticity (PSS)6
Botulinum toxin type A is a recommended option in the Royal College of Physicians National Guidelines (2018) - Spasticity in adults: management using botulinum toxin6
BOTOX® (botulinum toxin type A) is indicated for the symptomatic treatment of focal spasticity, including5:
- upper limb spasticity in adults
- ankle and foot disability due to lower limb spasticity in adults
Royal College of Physicians – Spasticity in adults: Management using botulinum toxin (National Guidelines 2018)6
Early intervention: When combined with rehabilitation, botulinum toxin has been shown to provide a sustained reduction in post-stroke upper-limb spasticity as early as 2–12 weeks post-stroke (Rosales, Kong et al 2012)
Multidisciplinary approach: Botulinum toxin should be used as part of a coordinated multidisciplinary approach, involving physical management and therapy
Role for physiotherapists and nurses: In accordance with UK statutes, appropriately experienced and qualified physiotherapists and nurses may be trained to prescribe and inject botulinum toxin; this may be highly cost-efficient
Secondary benefits: A successful treatment package can also prevent secondary complications such as impaired movement and difficulty maintaining hygiene and self-care
Core principles for intervention6
The principles for successful botulinum toxin intervention are:
Appropriate patient selection (e.g. dynamic spastic component as opposed to contracture)
Clear, realistic and worthwhile goals for treatment agreed with patients and families (e.g. pain relief; reduction of involuntary movements; mobility)
Establishment of the immediate and ongoing treatment programme
Adapted from Royal College of Physicians 20186
GAS: goal attainment setting; PSS: post-stroke spasticity; SMART: Specific, Measurable, Achievable, Realistic and Timed.
Please refer to the BOTOX® Summary of Product Characteristics for further information on adverse events, contraindications and special warnings and precautions for use. The BOTOX® Summary of Product Characteristics can be found here
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Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/ or via the MHRA Yellow Card app, available in the Google Play or Apple App Stores.
Adverse events should also be reported to AbbVie on GBPV@abbvie.com
Date of preparation: June 2025. UK-BTX-250067.
